姓名：张浪

职称：副研究员

学位：博士

邮箱：zhanglang@yfi.ac.cn

研究方向：水产品品质调控与鉴定

合作院校：长江大学兼职硕士研究生导师

教育经历

2011.09-2015.06，中北大学，生物医学工程，学士

2015.09-2020.06，武汉大学，遗传学，博士

主要职历

2020.07-2020.09，中国水产科学研究院长江水产研究所，实习

2020.10-2022.12，中国水产科学研究院长江水产研究所，助理研究员

2023.01-2024.09，中国水产科学研究院长江水产研究所，所聘副研究员

2024.10至今，中国水产科学研究院长江水产研究所，副研究员

科研成果

一、主要研究内容

　　主要从事水产品品质调控与鉴定研究，围绕水产品食品安全、品质提升、高品质种质创制开展工作。形成了以下三个研究方向：

1. 监测水产品风险物质，挖掘其抗积累分子靶标并阐明机制；

2. 研发水产品品质提升的关键技术，开发基于品质鉴定的精准甄别技术；

3. 挖掘特征品质相关分子靶标，发掘及创制高品质水产品新种质。

二、主持的科研项目

1. 湖北省重点研发计划项目，两个国审鲌鲂品种的品质提升关键技术及调控机制研究，2023.01-2025.12，50万，在研，主持；

2. 国家自然科学基金青年基金，ABCC2 转运蛋白在克氏原螯虾腹部肌肉中抗汞积累特性研究，2024.01-2026.12，30万，在研，主持；

3. 国家重点研发计划项目子课题，基于代谢组学的野生及养殖水产品精准鉴定技术研究，2022.10-2025.10，64万，在研，主持；

4. 国家科技重大专项子任务，少肌间刺鲤新种质创制及品质评价，2023.09-2025.12，60万，在研，主持；

5. 中国水产科学研究院长江水产研究所基本科研业务费专项项目，两个国审鲌鲂品种的高效聚硒技术研发及关联基因挖掘，2024.01-2024.12，5万，在研，主持；

6. 中国水产科学研究院长江水产研究所基本科研业务费专项项目，环境因子对克氏原螯虾肌肉品质影响的研究，2022.01-2023.12，10万，结题，主持。

三、2020-2024年发表的主要论文

1. Lang Zhang*,#, Ziwei Song#, Li He, Shan Zhong, Xiaoqian Ju, Hang Sha, Jing Xu, Qiuying Qin, Jie Peng*, Hongwei Liang*. Unveiling the toxicological effects and risks of prometryn on red swamp crayfish (Procambarus clarkii): Health assessments, ecological, and molecular insights. Science of The Total Environment, 2024, 951: 175512.

2. Lang Zhang#, Ziwei Song#, Shan Zhong*, Zongbin Cui*. Cloning of down-regulated genes under cold stress and identification of important genes related to cold tolerance in zebrafish (Danio rerio). Comparative Biochemistry and Physiology, Part A, 2024, 298: 111739.

3. Xing Lu*,#, Lang Zhang#, Gen-Mei Lin, Jian-Guo Lu, Zong-Bin Cui*. Analysis of differential gene expression under acute lead or mercury exposure in larval zebrafish using RNA-Seq. Animals, 2024, 14, 2877.

4. Zhou Shun, Chen Shengao, Xia Liwei, Dong Jing, Liu Yongtao, Yang Qiuhong, Zhang Lang*, Ai Xiaohui*. Efficacy and safety assessment of triclabendazole for treating Gyrodactylus infections in goldfish. Aquaculture, 2024, 584: 740640.

5. Zhang Lang#, Song Ziwei#, Zhou Yuntao#, Zhong Shan, Yu Yali, Liu Ting, Gao Xiaoping, Li Lekang, Kong Chiping, Wang Xinna, He Li*, Gan Jinhua*. The accumulation of toxic elements (Pb, Hg, Cd, As, and Cu) in red swamp crayfish (Procambarus clarkii) in Qianjiang and the associated risks to human health. Toxics, 2023, 11(7): 635.

6. Zhang Lang#, Wei Huijie#, Yu Yali, Li Qing, Song Ziwei, Sun Yanhong, Li Pei, Chen Jian, Gan Jinhua, Zhang Hui, Lu Xiaorong, Wang Guiying*, He Li*. Insights into the molecular mechanism of muscle textural quality improvement treated by exercise using comparative transcriptome analysis on the hybrid (Erythroculter ilishaeformis♀×Ancherythroculter nigrocauda♂). Aquaculture Reports, 2023, 31: 101672.

7. Zhang Lang, Zhou Yuntao, Song Ziwei, Liang Hongwei, Zhong Shan, Yu Yali, Liu Ting, Sha Hang, He Li, Gan Jinhua*. Mercury induced tissue damage, redox metabolism, ion transport, apoptosis, and intestinal microbiota change in red swamp crayfish (Procambarus clarkii): Application of multi-omics analysis in risk assessment of Hg. Antioxidants 2022, 11.

8. Zhang Lang, Song Ziwei, Zhong Shan, Gan Jinhua, Liang Hongwei, Yu Yali, Wu Gang, He Li*. Acute hypoxia and reoxygenation induces oxidative stress, glycometabolism, and oxygen transport change in red swamp crayfish (Procambarus clarkii): Application of transcriptome profiling in assessment of hypoxia. Aquaculture Reports 2022, 23, 101029.

9. Wei Huijie#, Zhang Lang#, Li Qing, Yu Yali, Sun Yanhong, Song Ziwei, Li Pei, Mao Tao, Chen Jian, He Li*, Guiying Wang*. Dynamic effects of short-term exercise on muscle texture and gut flora in the hybrid (Megalobrama amblycephala♀ × Ancherythroculter nigrocauda♂). Frontiers in Marine Science, 2022, 9:970858.

10. Zhang Lang, Li Xiaohui, Yu Yali, Zhang Lang, Dong Lixue, Gan Jinhua, Mao Tao, Liu Ting, Peng Jie, He Li*. Comparative analyses of liver transcriptomes reveal the effect of exercise on growth-, glucose metabolism-, and oxygen transport-related genes and signaling pathways in grass carp (Ctenopharyngodon idella). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2021, 262, 111081.

11. Zhang Lang, Yu Yali, Dong Lixue, Gan Jinhua, Mao Tao, Liu Ting, Li Xiaohui, He Li*. Effects of moderate exercise on hepatic amino acid and fatty acid composition, liver transcriptome, and intestinal microbiota in channel catfish (Ictalurus punctatus). Comp Biochem Physiol Part D Genomics Proteomics, 2021, 40, 100921.

12. Zhang Lang, Fang Yu, Lu Xing*, Xu Shanshan, Cai Fangfang, Yu Mengke, Li Xiaohui, Zhong Shan*. Transcriptional response of zebrafish larvae exposed to lindane reveals two detoxification genes of ABC transporter family (abcg5 and abcg8). Comparative Biochemistry And Physiology C-toxicology & Pharmacology, 2020, 232, 108755.

四、授权发明专利

1. 张浪,喻亚丽,王贵英,李清,何力,甘金华,孙艳红,宋紫薇,鲁晓蓉. 国家发明专利: 杂交鲌“先锋1号”于运动诱导下肌肉差异表达的标记基因及应用. 专利号：ZL202310918734.7

2. 张辉,张浪,段辛斌,宋紫薇,李罗新. 国家发明专利: 判别野生与养殖四大家鱼的有机酸类代谢标志物及用途. 专利号：ZL202410532118.2

备注

欢迎对水产品品质调控与鉴定、品质性状解析等研究感兴趣的同学加盟。